Outcomes in diabetics undergoing revascularization

EDITORIAL COMMENT Outcomes in Diabetics Undergoing Revascularization

Diabetes mellitus, a major determinant of cardiovascular events, portends an adverse prognosis in patients with coronary artery disease regardless of treatment strategy. Among patients undergoing coronary revascularization procedures, the Bypass Angioplasty Revascularization Investigation (BARI) trial (1) demonstrated an unfavorable interaction between diabetes and an initial strategy of percut...

Cardiovascular disease in diabetics: pharmacology and revascularization.

Diabetes has become a public health crisis. With the incidence of obesity rising in the United States, the number of diabetics will grow considerably. Of greatest concern is the impact this trend will have on cardiovascular disease. Diabetics demonstrate accelerated coronary atherosclerosis, and the prognosis is worse following cardiac events. Moreover, our interventions have achieved uneven su...

Coronary Revascularization in Diabetics: The Background for an Optimal Choice

NPH insulin-dependent diabetics undergoing cardiac catheterization

Protamine is widely used for reversing systemic heparinization after cardiac catheterization. Although rare, major reactions to protamine that simulate anaphylaxis occasionally occur and have previously been associated only with an allergic reaction to fish. Because neutral protamine Hagedorn (NPH) insulin includes protamine, it might be anticipated that NPH insulin-dependent diabetic patients ...

Influence of frailty and health status on outcomes in patients with coronary disease undergoing percutaneous revascularization.

BACKGROUND- Although older patients frequently undergo percutaneous coronary interventions (PCI), frailty, comorbidity, and quality of life are seldom part of risk prediction approaches. We assessed their incremental prognostic value over and above the risk factors in the Mayo Clinic risk score. METHODS AND RESULTS- Patients ≥65 years who underwent PCI were assessed for frailty (Fried criteria)...